Information Resources, LC

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Specialists in Chemical Analysis
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Mass Spectrometry

High Performance Liquid Chromatography/ Mass Spectrometry is now accessible and affordable. With on-line HPLC/MS, we can now analyze non-volatile, highly-polar, and thermally-labile compounds which can't be dealt with effectively by conventional HPLC or GC/MS methodology. Using multi-wavelength monitoring (diode array) together with mass spectrometry, our HPLC analysis achieves an unprecedented level of compound detection and identification. San Rafael Chemical Services provides quality analysis of the continually expanding array of compounds from pharmaceutical research, biotechnical and natural product development, and environmental protection. San Rafael's founder and director, Ralph Meibos, has been involved in the field of analytical chemistry for over twenty years. When HPLC/MS was commercially introduced, he immediately recognized the increase in analytical capability such instrumentation would provide and took the steps necessary to make this state-of-the-art service available.	Pharmaceutical and Bio-technical Applications The complexity of the compounds encountered in medicine, nutrition, and in the isolation and purification of natural or synthetic chemical products demands a level of sophistication in analytical expertise and instrumentation beyond the reach of most laboratories. Whether your need is the initial characterization of the principle components, the identification of impurities, or the determination of possible chemical or physiological interaction, San Rafael Chemical Services is prepared to provide the needed assistance toward meeting these types of research or regulatory requirements.
	Our goal at San Rafael Chemical Services is to keep pace with the rapid advances in analytical technology. We want to provide easier access to the information made available through these new techniques. By incorporating the most up-to-date, productive, conclusive, and cost effective means available, we are able to address the widest range of analytical applications possible.	Environmental Applications The number of compounds regulated by the EPA increases every year (by law). The most cost-effective way, and sometimes the only way to analyze samples for the presence of the contaminants being considered for regulation is by HPLC/MS. To date, drinking water method 553 and solid waste method 8321 have been established to utilize this instrumentation in order to monitor many classes of chemicals such as surfactants, azodyes and organophosphorus compounds, all known to have adverse effects on the environment. Features Particle Beam HPLC/MS - ThermoSpray HPLC/MS - In-Series Diode Array Detection - Direct Insertion Pyrolysis Probe - Capillary GC/MS - Cold On-column Injection Capability - Electron Impact Ionization Negative Chemical Ionization Positive Chemical Ionization Discharge Ionization NIST 75000 Entry Spectral Library 2000 amu Mass Range

HPLC/MS APPLICATIONS: Biologicals - nucleosides, amino acids, catacholamines, bile acids, aflatoxins, fatty acids, saccharides, hormones, dietary supplement component identification, natural synthetic and bio-engineered compound characterization. Pharmaceuticals - analgesics, antibiotics, xanthines, anesthetics, antidepressants, steroids, anti-tumor agents, vitamins, emulsifiers, anti-oxidants, metabolic fate determination and by-product formation studies.
Environmental Contaminants - warfare agents, explosives, carbonates, phenoxyacid herbicides, and fluorescent dyes, ionic and non-ionic surfactants, alkaloids, isocyanates, PNA's. Drugs of abuse - opiates, hallucinogenics, barbiturates, anabolic steroids, amphetamines.

Kombucha Analysis: San Rafael Chemical Services, Inc. has already analyzed over 1,100 Kombucha samples using HPLC/MS/PDAD.
To contact San Rafael Chemical Services about testing, use the information below. San Rafael Chemical Services is NOT affiliated with Kombucha-Research.com San Rafael Chemical Services 2180 E 4500 South Holladay, Utah 84117